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KMID : 0387820230300020075
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Clinical Pediatric Hematology-Oncology
2023 Volume.30 No. 2 p.75 ~ p.79
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Two Cases of Chronic Myeloid Leukemia in Lymphoid Blast Phase Presented as Philadelphia-Positive Acute Lymphoblastic Leukemia
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Lee Tae-Hoon
Ju Hee-Young
Lee Ji-Won
Sung Ki-Woong
Yoo Keon-Hee
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Abstract
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Patients with chronic myeloid leukemia (CML) in lymphoid blast phase can present clinical characteristics resembling Philadelphia chromosome-positive acute lympho-blastic leukemia (Ph+ ALL). It is crucial to distinguish between two diseases since their treatments differ. We present two cases of children who presented with CML lymphoid blast crisis, who were initially difficult to distinguish from Ph+ ALL.
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KEYWORD
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Chronic myeloid leukemia, Blast crisis, Philadelphia chromosome, Precursor cell lymphoblastic leukemia-lymphoma
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